Abstract:Objective To observe the status of cerebral glucose metabolism in normal control group mice,APP/PS1 double transgenic mice of model group and curcumin treatment group by 18F-FDG microPET.Methods APP/PS1 dtg mice from the model group,curcumin treatment group,and normal C57BL/6J mice with the same background were randomly selected(age: 6 months;n=3)for microPET study.Each mouse was anesthetized using 2% isoflurane and was injected through a tail vein with 14.8-16.5 MBq 18F-FDG as a bolus.After 45-minute of 18...