Abstract:Objective To explore the optimal dosage of 2-deoxy-glucose(2-DG) in the establishment of a mouse model of endoplasmic reticulum stress.Methodes 108 healthy male SD rats were choosen and randomly divided into 6 groups: sham-operation group,ischemia-reperfusion group,2-DG 50 mg /kg group,2-DG 100 mg /kg group,2-DG 150 mg /kg group,2-DG 200 mg /kg group,using different dosage of 2-DG to set up models of endoplasmic reticulum stress.2-DG was dissolved in double distilled water on working concentration of 50 mg ...