Expression and Significance of Cyclin A1 mRNA in the Skin of Wild-Type Mice
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KeyWord:cyclinA1;CyclinA1 mRNA;Skin;Sebaceous gland;Epidermis;In situ hybridization;Mice;wild-type
ZHU Xia,WEI Hong-quan,LI Yuan-hong,WU Yan,ZHAO Chen,GAO Xing-hua,CHEN Hong-duo
ZHU Xia~1,WEI Hong-quan~2,LI Yuan-hong~1,WU Yan~1,ZHAO Chen~2,GAO Xing-hua~1,CHEN Hong-duo~(1)
(1.Department of Dermatology,2.Department of Otorhinolaryngology,The First Affiliated Hospital of China Medical University,Shenyang 110001,China)
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      Objective To study the expression and significance of cyclin A1 in the skin of wild-type mice at RNA level.Methods Thirty 6-12-week old wild-type Kunming mice(15 male and 15 female) were included in this study.In situ hybridization was used to detect the expression of cyclin A1 mRNA in the skin of head and neck of the mice.The skin treated without probe was regarded as negative control and the testis of male mice was taken as positive control.Results The expression of cyclin A1 mRNA was found in sebaceous g...
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