The value of six blood enzymes and two plasma protein levels in spontaneous NIDDM Chinese hamster were measured and their relationships were determined. The results were: five blood enzymes and plasma total protein of NIDDM animals all have a higher level than those of control (P<0.01), which suggests that the spontaneous NIDDM inbredline Chinese hamsters pathogenesis glycaemia and protein metablic abnormality. Key words Blood enzyme Non-insulin-dependent-diabetic mellitus Chinese hamster$$$$Zhou Liqun (Department of Mechanical Engineering,Xiangtan University,Xiangtan,411105,China) Abstract The paper develops a mixed dispersed variable optimal method for multistage cylinder gear reduction box.Single stage optimization and total ratio distributing optimization consist of the whole optimizations by separating coupling relations of stages.