Campylobacter jejuni is a global concerned zoonosis pathogens. It can cause human and animals a variety of diseases if being infected. Animal models are the foundation of doing research on pathogenesis, vaccine evaluation and drug development. Considering the feasibility, economy and repeatability of animal models fastidious bacteria infected, Campylobacter jejuni has no appropriate animal models and its pathogenesis is unclear. This article will describe the experimental animal models for Campylobacter jejuni infections.