Objective To examine whether glucose intraperitoneal injection could successfully establish rat sugar cataract models. We also discussed the delay effect and short-term therapeutic effect of Baicalin eyedrop, taurine eyedrop, taurine intraperitoneal injection and Vc intraperitoneal injection on cataract models. Methods The study established cataract models using intraperitoneal injection of 30% glucose following the doses of 2.5ml/time for a male rat and 2ml/time for a female rat. We also provided all drugs at the same time, including eyedrops for twice a day, and intraperitoneal injection for once a day. We examined lens situation using slit-lamp from the third day of injection. We also measured body weight and diet situation during the study. Results The study showed that glucose intraperitoneal injection could establish sugar cataract in 3 days. The delay effect and short-term therapeutic effect of every drug had the same trandency, and they were taurine intraperitoneal injection > Baicalin eyedrop > taurine eyedrop > Vc intraperitoneal injection. Conclusions 30% Glucose intraperitoneal injection could induce rat sugar cataract in a short period. Further more, the delaying effect of taurine injection and Chinese traditional medicine Baicalin eyedrop were more obvious compared with taurine eyedrop and Vc injection.