Analysis of animal models of rheumatoid arthritis based on theories of traditional Chinese and Western medicine
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1. Yunnan University of Chinese Medicine, Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Kunming 650500, China. 2. School of Medicine, Jinan University, Guangzhou Key Laboratory of Germ-free Animals and Microbiota Application, Guanzhou 510632

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    Abstract:

    Rheumatoid arthritis ( RA ) is a complex autoimmune disease characterized by severe joint inflammation, synovial hyperplasia, and cartilage and bone destruction. Based on our understanding of RA and the theories of traditional Chinese and Western medicine, this paper presents the existing RA animal models and analyzes the modeling method , mechanisms, model evaluation indicators, clinical symptom coincidences, advantages and disadvantages, and model applicability to provide a reference for the establishment of better RA animal models.

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History
  • Received:May 17,2022
  • Revised:
  • Adopted:
  • Online: March 24,2023
  • Published: