Abstract:Miniature pigs are similar to humans in terms of their physiology, anatomy, nutrition, metabolism, drug metabolism, and disease development and are therefore widely used in the study of human disease. Chinese miniature pigs have stable genetics but are also outbred. However, the harnessing of the characteristics of Chinese miniature pigs in the establishment of mini-pig models of human disease that meet the needs of biomedical research is still in the exploratory stage. In this article, we summarize the status of the breeds of Chinese miniature pig with respect to research into human diseases in order to provide a reference and guidance for the further use of this species in the study of human diseases.