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| Research progress on establishing interstitial cystitis models |
| Received:August 22, 2019 |
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| DOI：10. 3969 / j.issn.1005-4847. 2020. 01. 022 |
| KeyWord:interstitial cystitis; bladder pain syndrome; animal models; pathogenesis; inflammation |
| Author | Institution |
| 昂小杰 |
苏州大学附属第一医院泌尿外科,江苏 苏州 |
| 李淼 |
苏州大学附属第一医院泌尿外科,江苏 苏州 |
| 周峰 |
苏州大学附属第一医院泌尿外科,江苏 苏州 |
| 蔡宗强 |
苏州大学附属第一医院泌尿外科,江苏 苏州 |
| 陈卫国 |
苏州大学附属第一医院泌尿外科,江苏 苏州 |
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| Abstract: |
| Interstitial cystitis (IC), also known as bladder pain syndrome, is a common urological disease. As the IC pathogenesis is complex, no standard animal model has been established for the comprehensive and in-depth study of IC. Current IC models include intravesical infusion of chemical drugs, intraperitoneal injection of cyclophosphamide, autoimmune cystitis, neurogenic inflammation and psychological and physiological stressors/ natural models. Each model has advantages and disadvantages. This paper reviews the research progress on animal models of IC. |
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