Research progress on establishing interstitial cystitis models
Received:August 22, 2019  
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DOI:10. 3969 / j.issn.1005-4847. 2020. 01. 022
KeyWord:interstitial cystitis; bladder pain syndrome; animal models; pathogenesis; inflammation
昂小杰 苏州大学附属第一医院泌尿外科,江苏 苏州
李淼 苏州大学附属第一医院泌尿外科,江苏 苏州
周峰 苏州大学附属第一医院泌尿外科,江苏 苏州
蔡宗强 苏州大学附属第一医院泌尿外科,江苏 苏州
陈卫国 苏州大学附属第一医院泌尿外科,江苏 苏州
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      Interstitial cystitis (IC), also known as bladder pain syndrome, is a common urological disease. As the IC pathogenesis is complex, no standard animal model has been established for the comprehensive and in-depth study of IC. Current IC models include intravesical infusion of chemical drugs, intraperitoneal injection of cyclophosphamide, autoimmune cystitis, neurogenic inflammation and psychological and physiological stressors/ natural models. Each model has advantages and disadvantages. This paper reviews the research progress on animal models of IC.
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