As an important component of laboratory animals, the applied research of laboratory fish has expanded to all fields of bioscience, making significant contributions to scientific research. The standardization study of quality control of laboratory fish has encountered issues due to complications regarding the source, generation, breeding, and management of laboratory fish. This paper reviews the current situation regarding the breeding, management, and standardization study of closed colony and inbred strains of laboratory fish at home and abroad. The paper also analyzes current problems, aiming at providing references for the breeding, management, and standardization study of quality control of laboratory fish in China.