Establishment and evaluation of animal models of steroid-induced avascular necrosis of the femoral head
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(1. Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China. 2. Department of Spinal Surgery,Affiliated Hospital of Traditional Chinese Medicine University, Lanzhou 730020)

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    Abstract:

    Owing to the widespread use of glucocorticoids, the incidence of steroid-induced avascular necrosis of the femoral head has increased year by year, but its pathogenesis and possible preventive measures are still unclear. To carry out in-depth research into its fundamental treatment, the establishment of an animal model of steroid-induced avascular necrosis of the femoral head will be the key to success. This paper reviews the research progress of modeling schemes, modeling animals and modeling standards.

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History
  • Received:March 31,2019
  • Revised:
  • Adopted:
  • Online: January 07,2020
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