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| Advances in Research on Sumoylation of Breast Cancer-Related Proteins |
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| DOI： |
| KeyWord:Sumoylation;ER signaling pathway;Co-regulator;Post-translational modifications;Breast cancer |
| QIU Wei-yi,YE Qi-nong |
QIU Wei-yi,YE Qi-nong(Beijing Institute of Biotechnology,Beijing 100850)
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| Abstract: |
| Small ubiquitin-like modifiers(SUMO) are a family of proteins that modulate important functional properties,including protein interaction,subcellular localization,protein dimerization,DNA binding and/or transactivation of transcription factors.It has been suggested that SUMO proteins may play an important role in breast carcinogenesis by sumoylation of estrogen signaling proteins such as co-regulators,and breast cancer-related proteins. |
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