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Effects of Resuscitation at 100% Oxygen Environment or Room Air Environment on the Ultrastructure of Neurons in the Cerebral Cortex of Hypoxic Neonatal Rat |
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DOI: |
KeyWord:Reoxygenation;Ultrastrueture;Neuron;cerebral cortex;Hypoxia;Neonatal rat |
GAO Xue-Song,WANG Zi-neng |
GAO Xue-Song,WANG Zi-neng (Department of Obstetrics & Gynecology,The First Affiliated Hospital of Jinan University,Guangzhou 510630,China)
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Abstract: |
Objective To compare the effects of resuscitation at pure oxygen environment(100% oxygen) or room air environment(21% oxygen) on the ultrastructure of cerebral cortical neurons in hypoxic neonatal rat.Methods Twenty Sprague-Dawley neonatal rats aged 7 days were divided into the pure oxygen environment(POE) and room air environment groups(RAE) after hypoxia,and each group was divided again into 24 h and 72 h subgroups.The pups were placed in an incubator containing 8% O_2 to be at acute hypoxia continued for... |
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