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| Bone Marrow Mesenchymal Stem Cell Transplantation in the Repair of Rat Spinal Cord Hemisection Injury |
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| DOI： |
| KeyWord:Bone marrow;Mesenchymal stem cells;Spinal cord injury;Induced differentiation;Cell transplantation;Rat |
| WU Jin-sheng,DONG Ai-ping,WANG Xiao-cui,WEI Zhi-xin,LIU Wei-guang,LUAN Zhi-min,ZHU Zeng-jun |
WU Jin-sheng~1,DONG Ai-ping~2,WANG Xiao-cui~3,WEI Zhi-xin~4,LIU Wei-guang~1,LUAN Zhi-min~1,ZHU Zeng-jun~1(1.Department of Urology,Affiliated Hospital of Weifang Medical College Weifang 261053,China,2.Lantian Hospital,Weifang 261042,3.Department of Human Anatomy,4.Laboratory of Morphology,Weifang Medical College,Weifang 261053)
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| Abstract: |
| Objective To investigate the differentiation of bone marrow-derived mesenchymal stem cells into neurons and transplantation of the stem cells to repair rat hemisection spinal cord injury.Methods Adherent culture was used to isolate and culture rat bone marrow mesenchymal stem cells(MSCs).The rat spinal cord homogenate supernatant was used to induce neural differentiation of the 3rd generation cells.The nature of cell differentiation was identified by immunohistochemistry.The rat model of hemisection spinal ... |
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