Establishment of a Minipig Model of Ischemic Heart Failure with Acute Myocardial Infarction by Coronary Balloon Occlusion and Injection of Intermixture of Microthrombi and Plastic Microspheres
  
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DOI:
KeyWord:Minipig;Acute myocardial infarction;Ischemic heart failure;Balloon occlusion;Intermixture of microthrombi and plastic microspheres;injection
ZHANG Jing,FU Xiang-hua,JIA Xin-wei,MA Ning,GU Xin-shun,JIANG Yun-fa,FAN Wei-ze,LIU Xiao-kun,FAN Xin-na
ZHANG Jing~1,FU Xiang-hua~1,JIA Xin-wei~1,MA Ning~1,GU Xin-shun~1,JIANG Yunfa~1,FAN Wei-ze~1,LIU Xiao-kun~1,FAN Xin-na~2(1.The Second Hospital of Hebei Medical University,Shijiazhuang 050000,China,2.The General Hospital of Hebei Province,Shijiazhuang 050000)
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Abstract:
      Objective To evaluate the method of establishment of a minipig model of ischemic heart failure(HF) with acute myocardial infarction(AMI) by coronary balloon occlusion and coadministration of injecting of microthrombi and plastic microspheres.Methods A total of eighteen minipigs were selected.After coronary angiography,angioplasty balloons were placed in the mid-distal of left anterior descending(LAD).The balloon was inflated intermittently to occlude the LAD 3 times and then to occlude it continuously for 1...
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