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| Comparison of the Effect of Different Establishment Methods on the Rat Models of Polycystic Ovary Syndrome |
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| DOI： |
| KeyWord:Establishment;models;Rat;Polycystic ovary syndrome;Hormones;Histology;ovary |
| YANG Zheng-wang,ZHOU Fang,TAN Zhen-yu,Xu Qiong-fang,ZHANG Shu-yi,ZHONG Fei,LI Lan,XIONG Juan,YU Xi-ming,LU Yao-bang |
YANG Zheng-wang~1,ZHOU Fang~2,TAN Zhen-yu~1,Xu Qiong-fang~2,ZHANG Shu-yi~2,ZHONG Fei~2,LI Lan~2,XIONG Juan~2,YU Xi-ming~2,LU Yao-bang~(3)
(1.The First Affiliated Hospital,2.The Graduate School,3.The College of Pharmaceutical Sciences of Hunan University of Traditional Chinese Medicine,Changsha 410007,China)
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| Abstract: |
| Objective To establish rat models of polycystic ovary syndrome(PCOS) induced by different methods,to assess the serum levels of several related hormones,to examine the morphological changes in the ovaries,and to discuss their significance.Methods Letrozol,sodium prasterone sulfate,or sodium prasterone sulfate combined with human chorionic gonadotropin were used to establish rat models of PCOS.Radioimmunoassay was used to measure the serum levels of luteinizing hormone(LH),follicle-stimulating hormone(FSH),e... |
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