Establishment and Evaluation of a Rat Atherosclerosis Model
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R-332

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    Abstract:

    Objective To establish a rat atherosclerosis(AS) model by immune injury and high-fat feeding.Methods The rat model was established by the following procedure: Wistar rats(body weight 130-150 g) aged 5 weeks were included in this study.The rats received intraperitoneal injection of ovalbumin(OVA) and i.v.injection of bovine serum albumin,and were fed with high-fat feed plus vitamine D_3 and drinking water added with ferrous sulfate(FeSO_4).The serum lipid level and blood biochemical indexes were monitered an...

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