Objective To evaluate the beneficial effects of a Chinese medicine,Goutengsan,on intelligence of mice.Methods Mice were randomly divided into 6 groups: 3 experimental groups,of which were daily administrated(i.g.) with Goutengsan extract at a high,middle and low dose,respectively.The model and control groups were administrated with distilled water,whereas mice receiving administration of aniracetam at 0.2 g/kg body weight served as a positive control.After continuous administration for 3 weeks,scopolamine,sodium nitrite,40% ethanol were used to establish models of acquirement disorder,stability disorder and reappearance disorder of memory,respectively.The intelligence-promoting effect of Goutengsan extract was examined by Y-labyrinth method.Results The Goutengsan extract significantly improved the above-mentioned three memory hindrance models,especially in the group of reappearance disorder of memory.Conclusion The Chinese medicine Goutengsan can considerably improve the learning and memory capacities and show apparent intelligencepromoting effect in animal learning and memory disorder models.