Abstract:Objective To study the Chinese herb M on influencing proliferation of endothelial cells and to elucidate its biological mechanism of vascularization. Methods The model of rabbit chest aorta endothelial cells was established in vitro, and rabbit sera with different concentration of the drug were prepared. The serum was added into 96 wells with endothelial cells in culture plate, and the proliferation of endothelial cells was measured with MTT colorimetry. Result the Chinese herb M can promote proliferation of endothelial cells.Conclusion The Chinese herb M may improve vascularization by promoting proliferation of endothelial cells.