ObjectiveCompared with Schmidt Criterion and the others, the authors studied the characteristics of acute necrotizing pancreatitis (ANP) in the rat model triggered with sodium taurocholate (biliary pancreatitis) in order to develop more precise and reasonable method of pathological evaluation in practice. Methods Forty -eight Sprague -Dawley (SD) rats were assigned into 3 different groups, i.e., treatment (16), ANP (21) and sham -operation (11). Acute necrotizing pancreatitis was triggered with injection of sodium taurocholate via the biliopancreatic duct. Schmidt Criterion was employed after modification for histopathological scoring to make sure the accuracy of different methods in evaluation, combined with transmission electronmicroscope. Results Autopsy of the rats showed large amounts of bloody ascites, the largest, 6% of the body weight. Severe hemorrhage and acinar necrosis, destroyed pancreatic lobules with lots of red blood cells between them were demonstrated under microscope. Inflammation, congestion and hemorrhage were also found in liver, heart, lungs and kidneys. Of the 4 parameters of the Schmidt Criterion, the difference of hemorrhage was not revealed significantly between groups, while the other 3, inflammation, edema and acinar necrosis, too elaborate and troublesome. We used the mean count of the red blood cells between pancreatic lobules or grade scoring and found out the significant difference of pancreatic hemorrhage. Conclusions 1. The bile salt model of acute necrotizing pancreatitis triggered with sodium taurocholate is characterized by large amounts of bloody ascites, severe hemorrhage and acinar necrosis, microthrombi in capillaries in pancreatic tissues, and injuries in multiple extra -pancreas organs; 2. On the basis of modification of 3 parameters in Schmidt criterion, i.e., edema, acinar necrosis and inflammation, and the mean count of red blood cells, we suggested a new criterion for more precise histopathological assessment.