Abstract:Through the study of literature retrieval related to sarcopenia, the modeling method and model evaluation scheme of sarcopenia mice were summarized. The operation methods, advantages and disadvantages, and application scope of the four modeling methods of drug injection, aging, muscle atrophy, and transgenic were reviewed. The evaluation methods of muscle function, muscle strength, and muscle endurance were summarized, and their advantages and disadvantages were compared to provide reference for the later research of sarcopenia.