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赵海玥,王雅晳,施依璐,段莎莎,赵捷,张璐,白天昊,张小杉.多模态超声在类风湿关节炎动物模型中的应用进展[J].中国实验动物学报,2022,30(6):861~866.

多模态超声在类风湿关节炎动物模型中的应用进展

Advances in the application of multimodal ultrasound in animal models of rheumatoid arthritis

投稿时间：2022-03-15

DOI：10. 3969 / j.issn.1005-4847. 2022. 06. 017

英文关键词:rheumatoid arthritis multimodal ultrasound animal model

基金项目:

作者	单位
赵海玥	内蒙古医科大学,呼和浩特 010110
王雅晳	内蒙古医科大学附属医院超声科,呼和浩特 010050
施依璐	内蒙古医科大学附属医院超声科,呼和浩特 010050
段莎莎	内蒙古医科大学附属医院超声科,呼和浩特 010050
赵捷	内蒙古医科大学附属医院超声科,呼和浩特 010050
张璐	内蒙古医科大学,呼和浩特 010110
白天昊	内蒙古医科大学,呼和浩特 010110
张小杉	内蒙古医科大学附属医院超声科,呼和浩特 010050

Author Name	Affiliation
ZHAO Haiyue	nner Mongolia Medical University, Hohhot 010110, China
WANG Yaxi	Department of Ultrasound, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050
SHI Yilu	Department of Ultrasound, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050
DUAN Shasha	Department of Ultrasound, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050
ZHAO Jie	Department of Ultrasound, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050
ZHANG Lu	nner Mongolia Medical University, Hohhot 010110, China
BAI Tianhao	nner Mongolia Medical University, Hohhot 010110, China
ZHANG Xiaoshan	Department of Ultrasound, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050

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中文摘要:

类风湿关节炎(rheumatoid arthritis,RA)是以滑膜炎为主要特征的慢性自身免疫性疾病,可导致关节畸形及功能障碍。 RA 动物模型能很好地模拟疾病发生发展的病理生理过程,广泛用于 RA 实验研究。多模态超声技术可以定性、定量诊断 RA,监测病情变化,评估药物疗效,引导局部给药及靶向治疗,为 RA 动物模型研究提供精准方法。该文综述了多模态超声在 RA 动物模型诊疗中的应用情况。

英文摘要:

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, which can lead to joint deformity and dysfunction. Animal models of RA simulate the pathological and physiological processes of its occurrence and development, and are widely used in RA studies. Multimodal ultrasound technology allows qualitative and quantitative diagnosis of RA, monitors changes in conditions, evaluates drug efficacy, and guides local administration and targeted therapy, providing an accurate evaluation method for research of RA animals. This article reviews the application of multimodal ultrasound in the diagnosis and treatment of RA animal models.

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