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姜宁,张亦文,黄红,陈善广,李莹辉,刘新民.大小鼠学习记忆行为实验方法分类概述[J].中国实验动物学报,2022,30(6):839~845.
大小鼠学习记忆行为实验方法分类概述
Overview of animal behavioral tests of learning and memory
投稿时间:2021-12-20  
DOI:10. 3969 / j.issn.1005-4847. 2022. 06. 014
中文关键词:  学习记忆  行为实验方法  大、小鼠
英文关键词:learning and memory  behavioral test  rats/ mice
基金项目:
作者单位
姜宁 中国医学科学院北京协和医学院药用植物研究所,北京 100193 
张亦文 中国医学科学院北京协和医学院药用植物研究所,北京 100193 
黄红 中国医学科学院北京协和医学院药用植物研究所,北京 100193 
陈善广 中国航天员科研训练中心人因工程重点实验室,北京 100094 
李莹辉 中国航天员科研训练中心人因工程重点实验室,北京 100094 
刘新民 1. 中国医学科学院北京协和医学院药用植物研究所,北京 100193
2. 宁波大学新药技术研究院,浙江 宁波 315000 
Author NameAffiliation
JIANG Ning Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China 
ZHANG Yiwen Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China 
HUANG Hong Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China 
CHEN Shanguang National Key Laboratory of Human Factors Engineering, China Astronaut Research and Training Center, Beijing 100094 
LI Yinghui National Key Laboratory of Human Factors Engineering, China Astronaut Research and Training Center, Beijing 100094 
LIU Xinmin 1.Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China. 2. Institute of Drug Discovery Technology,Ningbo University, Ningbo 315000. 3. National Key Laboratory of Human Factors Engineering, China Astronaut Research and Training Center, Beijing 100094 
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中文摘要:
      学习记忆发生机制复杂,表现形式多样,产生过程涉及到信号的识别和辩认、信息的获得、巩固、再现和再巩固等多个环节;记忆的信息又包括图象记忆、声音记忆、嗅觉记忆、空间位置记忆等;根据信息保存时间的长短,分为短时记忆与长时记忆。行为学实验是评价学习记忆的主要手段。迄今为止,科学家建立了多种大、小鼠行为实验方法用于学习记忆的评价。本文首次对学习记忆行为学实验方法进行了分类和概述,针对不同类型列举不同的评价方法,为基于行为实验的学习记忆研究、相关的产品研发提供参考。
英文摘要:
      The mechanisms involved in learning and memory are complex and the forms of expression are diverse. The process of learning and memory involves signal recognition, information acquisition, consolidation, reproduction, and reconsolidation. Memory information includes image memory, sound memory, olfactory memory, and spatial location memory. Information can be divided into short-term memory and long-term memory according to how long it is stored. Behavioral experiments are the main method to evaluate learning and memory. To date, scientists have established a variety of behavioral experimental method in rats and mice to evaluate learning and memory. In this paper, the experimental method of behavioral learning and memory are classified and summarized for the first time, and different evaluation method are listed for the different experimental types. Our review provides a reference for behavioral experiment-based learning and memory research, and related product development.
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