仔猪肠道微生物研究进展
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国家自然科学基金(No.31330075,No.31301989)。


Current understanding of the intestinal microbiota of piglets
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    摘要:

    肠道菌群在哺乳动物及人类健康的作用正日益受到重视。仔猪的健康生长需要一个动态平衡的肠道微生态环境。然而,在猪的生命周期中,从食管到直肠的微生物分布与组成存在时间和空间的变化。健康的肠道菌群具有促进猪的营养代谢,维持肠黏膜屏障,调节免疫应答,抑制病原菌感染等功能。多种因素对猪肠道菌群的形成与稳定具有重要的作用,包括分娩方式(经过产道或剖宫产)、幼龄时期饮食(母乳或配方饲料)、抗生素或抗生素样分子的使用等。本文主要从仔猪肠道微生物组成与定植、功能、影响肠道微生物的因素等方面论述了仔猪肠道微生物与仔猪肠道健康的关系,从而加深肠道微生物对维护仔猪肠道健康作用的认识。

    Abstract:

    The role of intestinal microbiota in mammals and humans are gaining increasing attention.The health of piglets requires a dynamically balanced intestinal microbiota.However,there are temporal and spatial changes in the distribution and composition of microbiota from the esophagus to the rectum during the life cycle of the pig.The intestinal microbiota has various beneficial functions in pig,like nutrient metabolism,intestinal mucosal barrier,immune responses and pathogen infection.A variety of factors play an important role in the formation and stabilization of intestinal microbiota,including the ways of delivery (vaginal or caesarean),the diet during infancy (breast milk or formula feeds) and the usage of antibiotics or antibiotic-like molecules.In this review,we mainly discussed the relationship between intestinal microbiota and the intestinal health of piglets from the aspects of the composition and colonization of intestinal microbiota,as well as the functions and influencing factors of intestinal microbiota,so as to further understanding the importance of intestinal microbiota in intestinal function of piglets.

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夏耀耀,任文凯,黄瑞林,曾本华,魏泓,印遇龙.仔猪肠道微生物研究进展[J].中国实验动物学报,2017,25(6):681~688.

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  • 收稿日期:2017-10-19
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  • 在线发布日期: 2017-12-16
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